产品货号:
Z28877
中文名称:
TEM4/ARHGEF17抗体
英文名称:
Anti-TEM4/ARHGEF17 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TEM4/ARHGEF17 Antibody |
指标别名 | TEM4;P164RHOGEF;p164-RhoGEF;KIAA0337;TEM4;Rho guanine nucleotide exchange factor 17;164kDa Rho-specific guanine-nucleotide exchange factor |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | IHC,IF,ELISA |
基因名称 | ARHGEF17 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human p164-RhoGEF |
计算分子量 | 222KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Rho GTPases,which are activated by specific guanine-nucleotide exchange factors (GEFs),play pivotal roles in several cellular functions.TEM4,encoding a protein containing 1510 amino acids,contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain.TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart.It couples tyrosine kinase signals with the activation of the rho/rac GTPases,thus leading to cell differentiation and/or proliferation.Elevated levels of TEM4,TEM5,TEM6,TEM7 and TEM7R were also raised in breast cancer tissues.TEM4 could also prove to be useful targets therapeutically. |
Uniprot ID | Q96PE2 |
基因名全称 | Rho guanine nucleotide exchange factor 17 |
蛋白名全称 | Rho guanine nucleotide exchange factor 17 |
推荐稀释比 | IHC 1:100~1:300 IF 1:200~1:1000 ELISA 1:5000 |
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